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規(guī)格	庫存	目錄價	會員專享價	數量
10 mg	In-stock	￥500.00	登錄后可見	- +
25 mg	In-stock	￥886.00	登錄后可見	- +
50 mg	In-stock	￥1568.00	登錄后可見	- +

規(guī)格

庫存

目錄價

會員專享價

數量

10 mg

In-stock

￥500.00

登錄后可見

- +

25 mg

In-stock

￥886.00

登錄后可見

- +

50 mg

In-stock

￥1568.00

登錄后可見

- +

基本信息

英文名稱	Laduviglusib (Synonyms: CHIR-99021; CT99021)
中文名稱	6-((2-((4-(2,4-二氯苯基)-5-(5-甲基-1H-咪唑-2-基)嘧啶-2-基)氨基)乙基)氨基)煙腈; 拉格魯西布
CAS號	252917-06-9
分子式	C22H18Cl2N8
分子量	465.34
MDL	MFCD11846251
外觀	Off-white to light brown powder
儲存條件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

安全信息

化學穩(wěn)定性	DMSO中的溶液可在-20°下穩(wěn)定儲存3個月。

產品詳情

Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.

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